Mouse Monoclonal Antibody to EIF2AK2 | ProMab 30680 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to EIF2AK2

catalog :

30680

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6H3A10

The same clone is also sold as:

Abnova: MAB12238
Novus Biologicals: NBP2-37242
Invitrogen: MA5-38515

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, flow cytometry

product information

Catalog :

30680

Title :

Mouse Monoclonal Antibody to EIF2AK2

Species :

Human;

Clone :

6H3A10;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

Immunogen :

Purified recombinant fragment of human EIF2AK2 (AA: 329-551) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. J Alzheimers Dis. 2010;21(4):1217-31.; 2. Mol Cells. 2011 Aug;32(2):167-72.

Type :

Monoclonal Antibody

MW :

62kDa

Aliases :

PKR; PRKR; EIF2AK1