Mouse Monoclonal Antibody to BAD | ProMab 30637 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to BAD

catalog :

30637

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1G5B3

The same clone is also sold as:

Invitrogen: MA5-38454

reactivity :

human

application :

western blot, ELISA, flow cytometry

product information

Catalog :

30637

Title :

Mouse Monoclonal Antibody to BAD

Species :

Human;

Clone :

1G5B3;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Immunogen :

Purified recombinant fragment of human BAD (AA: FULL(1-168)) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400

References :

1. Clin Cancer Res. 2011 Oct 1;17(19):6356-66.; 2. Mol Cancer Res. 2010 Aug;8(8):1116-25.

Type :

Monoclonal Antibody

MW :

18.4kDa

Aliases :

BBC2; BCL2L8