Mouse Monoclonal Antibody to BACE1 | ProMab 30625 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to BACE1

catalog :

30625

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3C1C3

The same clone is also sold as:

Novus Biologicals: NBP2-37261
Invitrogen: MA1-177
Abnova: MAB12256

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry, flow cytometry

product information

Catalog :

30625

Title :

Mouse Monoclonal Antibody to BACE1

Species :

Human; Mouse; Rat;

Clone :

3C1C3;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. ; ;

Immunogen :

Purified recombinant fragment of human BACE1 (AA: 112-324) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. J Neurochem. 2012 Jan;120 Suppl 1:62-70. ; 2. Eur J Neurosci. 2010 Oct;32(7):1223-38. ;

Type :

Monoclonal Antibody

MW :

55.7kDa

Aliases :

ASP2; BACE; HSPC104