Mouse Monoclonal Antibody to TIE1 | ProMab 30615 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to TIE1

catalog :

30615

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8D12B10

The same clone is also sold as:

Abnova: MAB12265
Novus Biologicals: NBP2-37270

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

30615

Title :

Mouse Monoclonal Antibody to TIE1

Species :

Human;

Clone :

8D12B10;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.r;

Immunogen :

Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Int J Oncol. 2007 Oct;31(4):893-7.r; 2. Cancer. 2002 Mar 1;94(5):1517-21.r;

Type :

Monoclonal Antibody

MW :

125kDa

Aliases :

TIE; JTK14