Mouse Monoclonal Antibody to ITGAM | ProMab 30567 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to ITGAM

catalog :

30567

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3A10H5

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

product information

Catalog :

30567

Title :

Mouse Monoclonal Antibody to ITGAM

Species :

Human;

Clone :

3A10H5;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. ;

Immunogen :

Purified recombinant fragment of human ITGAM (AA: 623-728) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000

References :

1. Ann Rheum Dis. 2012 Dec;71(12):2028-34. ; 2. J Infect Chemother. 2011 Apr;17(2):291-6.

Type :

Monoclonal Antibody

MW :

127.1kDa

Aliases :

CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6