Mouse Monoclonal Antibody to MAPK14 | ProMab 30566 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MAPK14

catalog :

30566

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10B11C8

The same clone is also sold as:

Novus Biologicals: NBP2-37312

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

30566

Title :

Mouse Monoclonal Antibody to MAPK14

Species :

Human; Mouse; Monkey; Rat;

Clone :

10B11C8;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. ; ; ;

Immunogen :

Purified recombinant fragment of human MAPK14 (AA: 299-360) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Cytokine. 2012 Oct;60(1):114-21. ; 2. Clin Cancer Res. 2012 Aug 1;18(15):4037-47. ;

Type :

Monoclonal Antibody

MW :

41.3kDa

Aliases :

RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA