Mouse Monoclonal Antibody to PTP4A2 | ProMab 30563 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PTP4A2

catalog :

30563

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5B6F4

The same clone is also sold as:

Invitrogen: MA5-31870

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30563

Title :

Mouse Monoclonal Antibody to PTP4A2

Species :

Human;

Clone :

5B6F4;

lsotype :

Mouse IgG2b

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. ;

Immunogen :

Purified recombinant fragment of human PTP4A2 (AA: 58-162) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Cancer Res. 2010 Nov 1;70(21):8959-67. ; 2. Blood Cells Mol Dis. 2010 Apr 15;44(4):209-14. ;

Type :

Monoclonal Antibody

MW :

19.1kDa

Aliases :

HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b