Mouse Monoclonal Antibody to CA9 | ProMab 30544 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to CA9

catalog :

30544

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10F7A8

reactivity :

human

application :

western blot, ELISA, flow cytometry

product information

Catalog :

30544

Title :

Mouse Monoclonal Antibody to CA9

Species :

Human;

Clone :

10F7A8;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. ;

Immunogen :

Purified recombinant fragment of human CA9 (AA: 37-186) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400

References :

1. Breast Cancer Res Treat. 2012 Nov;136(1):67-75. ; 2. Histol Histopathol. 2011 Oct;26(10):1279-86. ;

Type :

Monoclonal Antibody

MW :

49.7kDa

Aliases :

MN; CAIX