Mouse Monoclonal Antibody to GPNMB | ProMab 30520 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to GPNMB

catalog :

30520

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7C10E5

The same clone is also sold as:

Novus Biologicals: NBP2-37351
Abcam: ab175427
Invitrogen: MA5-38532

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

30520

Title :

Mouse Monoclonal Antibody to GPNMB

Species :

Human;

Clone :

7C10E5;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. ;

Immunogen :

Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Prostate. 2012 Sep 15;72(13):1431-42. ; 2. Melanoma Res. 2010 Jun;20(3):184-90. ;

Type :

Monoclonal Antibody

MW :

64kDa

Aliases :

NMB; HGFIN