Mouse Monoclonal Antibody to MCAM | ProMab 30505 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MCAM

catalog :

30505

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6C3E6

The same clone is also sold as:

Novus Biologicals: NBP2-37365

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, flow cytometry

product information

Catalog :

30505

Title :

Mouse Monoclonal Antibody to MCAM

Species :

Human;

Clone :

6C3E6;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. ; ;

Immunogen :

Purified recombinant fragment of human MCAM (AA: 84-189) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. Cancer Lett. 2013 Apr 28;330(2):150-62. ; 2. J Biol Chem. 2013 Jan 25;288(4):2571-9. ;

Type :

Monoclonal Antibody

MW :

71.6kDa

Aliases :

CD146; MUC18