Mouse Monoclonal Antibody to EGFR mutant | ProMab 30486P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to EGFR mutant

catalog :

30486P

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5G9B5

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, flow cytometry

product information

Catalog :

30486P

Title :

Mouse Monoclonal Antibody to EGFR mutant

Species :

Human;

Clone :

5G9B5;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. ;

Immunogen :

Purified recombinant fragment of human EGFR mutant (AA: 693-893) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. J Immunol. 2012 Dec 1;189(11):5230-9. ; 2. J Biol Chem. 2012 Oct 12;287(42):35201-11. ;

Type :

Monoclonal Antibody

MW :

175kDa

Aliases :

ERBB; HER1; mENA; ERBB1; PIG61