Mouse Monoclonal Antibody to ALDH2 | ProMab 30471A product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to ALDH2

catalog :

30471A

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4G6A3

The same clone is also sold as:

Invitrogen: MA5-17029
Bio-Rad: VMA00235
Novus Biologicals: NBP2-37397

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30471A

Title :

Mouse Monoclonal Antibody to ALDH2

Species :

Human; Mouse; Rat;

Clone :

4G6A3;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms. ; ; ;

Immunogen :

Purified recombinant fragment of human ALDH2 (AA: 317-517) expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/150; FCM: 1/200 - 1/400

References :

1.Eur Heart J. 2012 Jul;33(13):1606-14. ; 2.Clin Toxicol (Phila). 2012 Apr;50(4):242-9. ;

Type :

Monoclonal Antibody

MW :

56.3kDa

Aliases :

ALDM; ALDHI; ALDH-E2