Mouse Monoclonal Antibody to CDH5 | ProMab 30447P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to CDH5

catalog :

30447P

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3D5C7

The same clone is also sold as:

Novus Biologicals: NBP2-37420
Invitrogen: MA5-17050

reactivity :

human, rat

application :

western blot, ELISA, flow cytometry

product information

Catalog :

30447P

Title :

Mouse Monoclonal Antibody to CDH5

Species :

Human; Rat;

Clone :

3D5C7;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. ; ;

Immunogen :

Purified recombinant fragment of human CDH5 (AA: 29-223 ) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400

References :

1.Blood. 2011 Feb 24;117(8):2515-26. ; 2.J Virol. 2010 Nov;84(21):11227-34. ;

Type :

Monoclonal Antibody

MW :

87.5kDa

Aliases :

7B4; CD144