Mouse Monoclonal Antibody to BMPR1A | ProMab 30446A product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to BMPR1A

catalog :

30446A

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4B7B2

The same clone is also sold as:

Invitrogen: MA5-17036
MyBioSource: MBS249195
Novus Biologicals: NBP2-37421
Abnova: MAB12496

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30446A

Title :

Mouse Monoclonal Antibody to BMPR1A

Species :

Human; Mouse;

Clone :

4B7B2;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. ; ;

Immunogen :

Purified recombinant fragment of human BMPR1A (AA: 179-378 ) expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1.Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1;67(Pt 5):551-5. ; 2.Gastroenterology. 2011 Jul;141(1):e23-6. ;

Type :

Monoclonal Antibody

MW :

60kDa

Aliases :

ALK3; SKR5; CD292; ACVRLK3; 10q23del