Mouse Monoclonal Antibody to MMP2 | ProMab 30440 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MMP2

catalog :

30440

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4D1E2

The same clone is also sold as:

Invitrogen: MA5-17122

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30440

Title :

Mouse Monoclonal Antibody to MMP2

Species :

Human;

Clone :

4D1E2;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. ; ;

Immunogen :

Purified recombinant fragment of human MMP2 (AA: 242-396) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1.Br J Cancer. 2012 Apr 24;106(9):1495-8. ; 2.Iran J Immunol. 2011 Jun;8(2):120-6. ;

Type :

Monoclonal Antibody

MW :

73.8kDa

Aliases :

CLG4; MONA; CLG4A; TBE-1; MMP-II