Mouse Monoclonal Antibody to STAT5A | ProMab 30423 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to STAT5A

catalog :

30423

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6D4

The same clone is also sold as:

Novus Biologicals: NBP2-37441
Invitrogen: MA5-17183

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30423

Title :

Mouse Monoclonal Antibody to STAT5A

Species :

Human;

Clone :

6D4;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. ; ;

Immunogen :

Purified recombinant fragment of human STAT5A (AA: 583-794 ) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: Propose dilution 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/50; FCM: 1/200 - 1/400

References :

1.Cancer Res. 2011 May 15;71(10):3720-31. ; 2.Blood. 2011 Mar 24;117(12):3409-20. ;

Type :

Monoclonal Antibody

MW :

90.6kDa

Aliases :

MGF; STAT5