Mouse Monoclonal Antibody to RUNX3 | ProMab 30408 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to RUNX3

catalog :

30408

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B3

The same clone is also sold as:

Bio-Rad: VMA00121
Abcam: ab135248
Invitrogen: MA5-17169
Novus Biologicals: NBP2-37455

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30408

Title :

Mouse Monoclonal Antibody to RUNX3

Species :

Human; Mouse;

Clone :

2B3;

lsotype :

Mouse IgG2b

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. Coli.

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1.J Cancer Res Clin Oncol. 2011 Dec;137(12):1823-30. 2.Oncogene. 2012 Jan 26;31(4):527-34.

Type :

Monoclonal Antibody

MW :

44.4kDa

Aliases :

AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070