Mouse Monoclonal Antibody to TGFb1 | ProMab 30383 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to TGFb1

catalog :

30383

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

'7F6

The same clone is also sold as:

Invitrogen: MA5-17186
Novus Biologicals: NBP2-22114, NBP2-80827

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, flow cytometry

product information

Catalog :

30383

Title :

Mouse Monoclonal Antibody to TGFb1

Species :

Human

Clone :

7F6;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease

Immunogen :

Purified recombinant fragment of human TGFb1 (AA: 62-195) expressed in E. Coli. ; ;

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1.Cell. 2011 Oct 28;147(3):565-76. ; 2.Kobe J Med Sci. 2011 May 11;56(6):E242-52. ;

Type :

Monoclonal Antibody

MW :

44.3kDa

Aliases :

CED; LAP; DPD1; TGFB; TGFbeta