Mouse Monoclonal Antibody to PDX1 | ProMab 30344 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PDX1

catalog :

30344

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

#2G12

The same clone is also sold as:

OriGene: AM06757PU-N
Abnova: MAB17873
Novus Biologicals: NBP2-37504
Invitrogen: MA5-38593

reactivity :

human

application :

western blot, ELISA, flow cytometry

product information

Catalog :

30344

Title :

Mouse Monoclonal Antibody to PDX1

Species :

Human

Clone :

2G12;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Immunogen :

Purified recombinant fragment of human PDX1 expressed in E. Coli. ;

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400

References :

Am J Clin Pathol. 2011 Feb;135(2):253-61. ; Pancreas. 2010 Aug;39(6):856-62. ; ;

Type :

Monoclonal Antibody

MW :

30.8kDa

Aliases :

GSF; IPF1; IUF1; IDX-1; MODY4; PDX-1; STF-1