Mouse Monoclonal Antibody to HEXA | ProMab 30343 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to HEXA

catalog :

30343

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3F10

The same clone is also sold as:

OriGene: AM06756PU-N
Novus Biologicals: NBP2-37505
Invitrogen: MA5-17089

reactivity :

human

application :

western blot, ELISA, flow cytometry

product information

Catalog :

30343

Title :

Mouse Monoclonal Antibody to HEXA

Species :

Human

Clone :

3F10;

lsotype :

Mouse IgG2b

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

Immunogen :

Purified recombinant fragment of human HEXA expressed in E. Coli. ;

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400

References :

Clin Biochem. 2009 Jul;42(10-11):1187-9. ; Pediatr Res. 2010 Feb;67(2):217-20. ;

Type :

Monoclonal Antibody

MW :

60.7kDa

Aliases :

TSD