Mouse Monoclonal Antibody to LRP5 | ProMab 30336 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to LRP5

catalog :

30336

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2B11

The same clone is also sold as:

OriGene: AM06765PU-N
Invitrogen: MA5-17113
Abnova: MAB17714

reactivity :

human

application :

western blot, ELISA, flow cytometry

product information

Catalog :

30336

Title :

Mouse Monoclonal Antibody to LRP5

Species :

Human

Clone :

2B11;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Immunogen :

Purified recombinant fragment of human LRP5 expressed in E. Coli. ;

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400

References :

1. Bone. 2010 Apr;46(4):940-5. ; 2. Endocr J. 2009;56(4):625-31. ;

Type :

Monoclonal Antibody

MW :

179kDa

Aliases :

HBM; LR3; OPS; EVR1; EVR4; LRP7; OPPG; BMND1; OPTA1; VBCH2