This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ProMab
product type :
antibody
product name :
Mouse Monoclonal Antibody to UBB
catalog :
30317
quantity :
0.1 mg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3C1.2

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, flow cytometry
product information
Catalog :
30317
Title :
Mouse Monoclonal Antibody to UBB
Species :
Human
Clone :
3C12;
lsotype :
Mouse IgG1
Size :
0.1 mg
Storage :
4℃; -20℃ for long term storage
Description :
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
Immunogen :
Purified recombinant fragment of human UBB expressed in E. Coli. ;
Formulation :
Purified antibody in PBS with 0.05% sodium azide
Applications :
ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
References :
1. Science. 2009 Aug 14;325(5942):834-40. ; 2. Biochem Soc Trans. 2009 Oct;37(Pt 5):937-53. ;
Type :
Monoclonal Antibody
MW :
26kDa
Aliases :
UBC; UBA52; RPS27A
company information
ProMab
5221 Central Avenue, Suite 200
Richmond, CA 94804
info@promab.com
http://www.promab.com
1-866-339-0871
headquarters: USA