Mouse Monoclonal Antibody to SKP1 | ProMab 30316 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to SKP1

catalog :

30316

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1H9

The same clone is also sold as:

Abnova: MAB10320
Invitrogen: MA5-17174
OriGene: AM06720SU-N

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, flow cytometry

product information

Catalog :

30316

Title :

Mouse Monoclonal Antibody to SKP1

Species :

Human

Clone :

1H9;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Immunogen :

Purified recombinant fragment of human SKP1 expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide. ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1.J Biol Chem. 2008 Nov 7;283(45):30796-803. ; 2.Cell. 2009 Jul 23;138(2):389-403. ;

Type :

Monoclonal Antibody

MW :

19kDa

Aliases :

OCP2; p19A; EMC19; SKP1A; OCP-II; TCEB1L