Mouse Monoclonal Antibody to CYP1A1 | ProMab 30312 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to CYP1A1

catalog :

30312

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6G5

The same clone is also sold as:

OriGene: AM06716PU-N
Abnova: MAB16333, MAB10576
Novus Biologicals: NBP2-37526
Invitrogen: MA5-17063

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

30312

Title :

Mouse Monoclonal Antibody to CYP1A1

Species :

Human

Clone :

6G5;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

Immunogen :

Purified recombinant fragment of human CYP1A1 expressed in E. Coli. ;

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Cancer Res. 2009 Apr 1;69(7):2956-65. ; 2. Drug Metab Lett. 2009 Jan;3(1):18-27. ;

Type :

Monoclonal Antibody

MW :

58kDa

Aliases :

AHH; AHRR; CP11; CYP1; P1-450; P450-C; P450DX