Mouse Monoclonal Antibody to TNNI2 | ProMab 30300 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to TNNI2

catalog :

30300

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2F12G2

The same clone is also sold as:

Novus Biologicals: NBP2-37536
Invitrogen: MA5-17189
Abnova: MAB10339
OriGene: AM06710PU-N

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, flow cytometry

product information

Catalog :

30300

Title :

Mouse Monoclonal Antibody to TNNI2

Species :

Human

Clone :

2F12G2;

lsotype :

Mouse IgG1

Size :

0.1 mg

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

Immunogen :

Purified recombinant fragment of human TNNI2 expressed in E. Coli. ;

Formulation :

Purified antibody in PBS with 0.05% sodium azide

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. Am J Hum Genet. 2009 Nov;85(5):628-42. ; 2. Cell Motil Cytoskeleton. 2008 Aug;65(8):652-61. ;

Type :

Monoclonal Antibody

MW :

21kDa

Aliases :

DA2B; FSSV; fsTnI; AMCD2B