Mouse Monoclonal Antibody to KCNQ1 | ProMab 30297 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to KCNQ1

catalog :

30297

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5E12

The same clone is also sold as:

OriGene: AM06707SU-N
Abnova: MAB10709
Invitrogen: MA5-17105

reactivity :

human

application :

western blot, ELISA, flow cytometry

product information

Catalog :

30297

Title :

Mouse Monoclonal Antibody to KCNQ1

Species :

Human

Clone :

5E12;

lsotype :

Mouse IgG2b

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.

Immunogen :

Purified recombinant fragment of human KCNQ1 expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide. ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400

References :

1. Biochem Biophys Res Commun. 2009 May 29;383(2):206-9. ; 2. J Biol Chem. 2009 Jun 12;284(24):16452-62. ;

Type :

Monoclonal Antibody

MW :

95kDa

Aliases :

LQT; RWS; WRS; LQT1; SQT2; ATFB1; ATFB3; JLNS1; KCNA8; KCNA9; Kv1.9; Kv7.1; KVLQT1; FLJ26167