Mouse Monoclonal Antibody to GSTM1 | ProMab 30295 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to GSTM1

catalog :

30295

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1H4A4

The same clone is also sold as:

OriGene: AM06705SU-N
Abnova: MAB10673
Invitrogen: MA5-31757

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, flow cytometry

product information

Catalog :

30295

Title :

Mouse Monoclonal Antibody to GSTM1

Species :

Human; Monkey

Clone :

1H4A4;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

Immunogen :

Purified recombinant fragment of human GSTM1 expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide. ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. J Exp Clin Cancer Res. 2009 Apr 1;28:46. ; 2. Cancer Prev Res (Phila). 2009 Apr;2(4):345-52. ;

Type :

Monoclonal Antibody

MW :

26kDa

Aliases :

MU; H-B; GST1; GTH4; GTM1; MU-1; GSTM1-1; MGC26563; GSTM1a-1a; GSTM1b-1b