Mouse Monoclonal Antibody to NQO1 | ProMab 30293 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to NQO1

catalog :

30293

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1.A.11

The same clone is also sold as:

OriGene: AM06703SU-N
Abnova: MAB10836
Invitrogen: MA5-15927

reactivity :

human

application :

western blot, ELISA, flow cytometry

product information

Catalog :

30293

Title :

Mouse Monoclonal Antibody to NQO1

Species :

Human

Clone :

1A11;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Immunogen :

Purified recombinant fragment of human NQO1 expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide. ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400

References :

1. Mol Cancer Ther. 2009 Dec;8(12):3369-78. ; 2. J Biol Chem. 2009 Nov 27;284(48):33233-41.

Type :

Monoclonal Antibody

MW :

31kDa

Aliases :

DTD; QR1; DHQU; DIA4; NMOR1; NMORI