Mouse Monoclonal Antibody to BMI1 | ProMab 30285 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to BMI1

catalog :

30285

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3E3

The same clone is also sold as:

Abnova: MAB10506
Invitrogen: MA5-15919

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30285

Title :

Mouse Monoclonal Antibody to BMI1

Species :

Human;

Clone :

3E3;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Immunogen :

Purified recombinant fragment of human BMI1 expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. Mol Cancer. 2009 Nov 10;8:98. ; 2. Cancer Res. 2009 Dec 1;69(23):9090-5. ;

Type :

Monoclonal Antibody

MW :

37kDa

Aliases :

PCGF4; RNF51; MGC12685; FLVI2/BMI1