Mouse Monoclonal Antibody to MSH6 | ProMab 30283 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MSH6

catalog :

30283

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5B11

The same clone is also sold as:

Abnova: MAB12506
Invitrogen: MA5-15917
OriGene: AM06693SU-N

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30283

Title :

Mouse Monoclonal Antibody to MSH6

Species :

Human;

Clone :

5B11;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer.

Immunogen :

Purified recombinant fragment of human MSH6 expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. J Biol Chem. 2009 Dec 11;284(50):34531-7. ; 2. J Biomed Sci. 2009 Oct 23;16:97. ;

Type :

Monoclonal Antibody

MW :

160kDa

Aliases :

GTBP; HSAP; HNPCC5