Mouse Monoclonal Antibody to DLK1 | ProMab 30280 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to DLK1

catalog :

30280

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3A10

The same clone is also sold as:

Invitrogen: MA5-15915
Novus Biologicals: NBP2-37548
Abnova: MAB10627
Abcam: ab119930
OriGene: AM06690SU-N

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, flow cytometry

product information

Catalog :

30280

Title :

Mouse Monoclonal Antibody to DLK1

Species :

Human;

Clone :

3A10;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.

Immunogen :

Purified recombinant fragment of human DLK1 expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. Epigenetics. 2009 Oct 1;4(7):469-75. ; 2. Mol Biol Cell. 2009 Jul;20(14):3353-62. ;

Type :

Monoclonal Antibody

MW :

41kDa

Aliases :

DLK; FA1; ZOG; pG2; PREF1; Pref-1