Mouse Monoclonal Antibody to PGC-1alpha | ProMab 30265 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PGC-1alpha

catalog :

30265

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1G8

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30265

Title :

Mouse Monoclonal Antibody to PGC-1alpha

Species :

Human

Clone :

1G8;

lsotype :

Mouse IgG2b

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Immunogen :

Purified recombinant fragment of human PGC-1alpha expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Diabetes Res Clin Pract. 2009 Dec;86(3):168-72. ; 2.Cell Metab. 2009 Sep;10(3):189-98. ;

Type :

Monoclonal Antibody

MW :

91kDa

Aliases :

PPARGC1A; LEM6; PGC1; PGC1A; PGC-1v; PPARGC1; PGC-1(alpha)