Mouse Monoclonal Antibody to KIT | ProMab 30259 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to KIT

catalog :

30259

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1C5

The same clone is also sold as:

Abnova: MAB10712
OriGene: AM06670SU-N
Invitrogen: MA5-15894

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

30259

Title :

Mouse Monoclonal Antibody to KIT

Species :

Human

Clone :

1C5;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell prolif- eration, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto- oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.

Immunogen :

Purified recombinant fragment of human KIT expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Curr Hematol Malig Rep. 2009 Apr;4(2):77-82. ; 2. Georgian Med News. 2010 Mar;(180):13-9. ;

Type :

Monoclonal Antibody

MW :

145kDa

Aliases :

PBT; SCFR; C-Kit; CD117