Mouse Monoclonal Antibody to PINCH | ProMab 30241 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PINCH

catalog :

30241

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5G7

The same clone is also sold as:

Invitrogen: MA5-15876
OriGene: AM06652SU-N
Abnova: MAB10297
Cell Signaling Technology: 11890
Novus Biologicals: NBP2-37581

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, flow cytometry

product information

Catalog :

30241

Title :

Mouse Monoclonal Antibody to PINCH

Species :

Human

Clone :

5G7;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Purified recombinant fragment of human PINCH expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. J Biol Chem. 2009 Feb 27;284(9):5836-44. ; 2. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20677-82.

Type :

Monoclonal Antibody

MW :

37kDa

Aliases :

PINCH; PINCH1; PINCH-1; LIMS1