Mouse Monoclonal Antibody to BLNK | ProMab 30232 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to BLNK

catalog :

30232

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5G9

The same clone is also sold as:

Abnova: MAB10505
OriGene: AM06644SU-N
Invitrogen: MA5-15868
Novus Biologicals: NBP2-37585

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog :

30232

Title :

Mouse Monoclonal Antibody to BLNK

Species :

Human; Mouse

Clone :

5G9;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Purified recombinant fragment of human BLNK expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. J Biol Chem. 2009 Apr 10;284(15):9804-13. ; 2. Cancer Sci. 2008 Dec;99(12):2444-54.

Type :

Monoclonal Antibody

MW :

68kDa

Aliases :

AGM4; BASH; LY57; SLP65; BLNK-S; SLP-65; MGC111051