Mouse Monoclonal Antibody to CRKL | ProMab 30231 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to CRKL

catalog :

30231

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5E12

The same clone is also sold as:

Invitrogen: MA5-15867
Abnova: MAB10613
OriGene: AM06643SU-N

reactivity :

human

application :

western blot, ELISA, flow cytometry

product information

Catalog :

30231

Title :

Mouse Monoclonal Antibody to CRKL

Species :

Human

Clone :

5E12;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Immunogen :

Purified recombinant fragment of human CRKL expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400

References :

1. Mol Cell Biol. 2009 Jun;29(11):3076-87. ; 2. Cell. 2009 Jul 23;138(2):389-403.

Type :

Monoclonal Antibody

MW :

39kDa

Aliases :

CRKL