Mouse Monoclonal Antibody to MYC | ProMab 30209 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MYC

catalog :

30209

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7E10

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30209

Title :

Mouse Monoclonal Antibody to MYC

Species :

Human

Clone :

7E10;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. (provided by RefSeq).

Immunogen :

Purified recombinant fragment of human MYC expressed in E. Coli. ;

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Mol Cell. 2009 Sep 11;35(5):610-25. ; 2. Clin Immunol. 2009 Dec;133(3):324-32.

Type :

Monoclonal Antibody

MW :

49kDa

Aliases :

MRTL; c-Myc; bHLHe39