This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
ProMab
product type :
antibody
product name :
Mouse Monoclonal Antibody to EIF4E
catalog :
30189
quantity :
100μl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5D11

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry
product information
Catalog :
30189
Title :
Mouse Monoclonal Antibody to EIF4E
Species :
Human
Clone :
5D11;
lsotype :
Mouse IgG1
Size :
100μl
Storage :
4℃; -20℃ for long term storage
Description :
eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.
Immunogen :
Purified recombinant fragment of human EIF4E expressed in E. Coli. ;
Formulation :
Ascitic fluid containing 0.03% sodium azide.
Applications :
ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
References :
1. Ann Surg Oncol. 2008 Nov;15(11):3207-15. ; 2. J Biol Chem. 2008 Sep 12;283(37):25227-37.
Type :
Monoclonal Antibody
MW :
25kDa
Aliases :
CBP; EIF4F; EIF4E1; EIF4EL1; MGC111573; EIF4E
company information
ProMab
5221 Central Avenue, Suite 200
Richmond, CA 94804
info@promab.com
http://www.promab.com
1-866-339-0871
headquarters: USA