Mouse Monoclonal Antibody to MSI2 | ProMab 30178 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MSI2

catalog :

30178

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2C11

The same clone is also sold as:

OriGene: AM06591SU-N
Abnova: MAB10815
Invitrogen: MA5-15821

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

30178

Title :

Mouse Monoclonal Antibody to MSI2

Species :

Human

Clone :

2C11;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.

Immunogen :

Purified recombinant fragment of human MSI2 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Am J Hum Genet. 2009 Nov;85(5):628-42. ; 2. Haematologica. 2008 Dec;93(12):1903-7.

Type :

Monoclonal Antibody

MW :

35kDa

Aliases :

MSI2H; MGC3245; FLJ36569; MSI2