Mouse Monoclonal Antibody to PRKDC | ProMab 30170 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PRKDC

catalog :

30170

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

'3H6

The same clone is also sold as:

OriGene: TA336925
Cell Signaling Technology: 12311
Invitrogen: MA5-15813
Novus Biologicals: NBP2-22128
Abnova: MAB10303

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

Catalog :

30170

Title :

Mouse Monoclonal Antibody to PRKDC

Species :

Human

Clone :

3H6;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.

Immunogen :

Purified recombinant fragment of human PRKDC expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000

References :

1. J Biol Chem. 2008 Dec 26;283(52):36311-20. ; 2. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12791-6.

Type :

Monoclonal Antibody

MW :

46.9kDa

Aliases :

HYRC; p350; DNAPK; DNPK1; HYRC1; XRCC7; DNA-PKcs; PRKDC