Mouse Monoclonal Antibody to MAP2K4 | ProMab 30168 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MAP2K4

catalog :

30168

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5H4

The same clone is also sold as:

OriGene: AM06580SU-N
Invitrogen: MA5-15811
Abnova: MAB10793

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, flow cytometry

product information

Catalog :

30168

Title :

Mouse Monoclonal Antibody to MAP2K4

Species :

Human

Clone :

5H4;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.Tissue specificity: Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues .

Immunogen :

Purified recombinant fragment of human MAP2K4 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. J Biol Chem. 2009 Jan 2;284(1):685-95. ; 2. J Immunol. 2008 Sep 1;181(5):3252-8.

Type :

Monoclonal Antibody

MW :

42kDa

Aliases :

JNKK; MEK4; MKK4; SEK1; JNKK1; SERK1; MAPKK4; PRKMK4; MAP2K4