Mouse Monoclonal Antibody to MAP2K6 | ProMab 30166 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to MAP2K6

catalog :

30166

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3H12B9

The same clone is also sold as:

OriGene: AM06578SU-N
Abnova: MAB10795
Invitrogen: MA5-15809

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

30166

Title :

Mouse Monoclonal Antibody to MAP2K6

Species :

Human; Mouse

Clone :

3H12B9;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas.

Immunogen :

Purified recombinant fragment of human MAP2K6 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. J Mol Med. 2008 Apr;86(4):485-90. ; 2. Blood. 2007 Jan 1;109(1):185-93.

Type :

Monoclonal Antibody

MW :

38kDa

Aliases :

MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; MAP2K6