Mouse Monoclonal Antibody to PSIP1 | ProMab 30152 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to PSIP1

catalog :

30152

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6E4

The same clone is also sold as:

OriGene: AM06564SU-N
Abnova: MAB10305
Invitrogen: MA5-15795

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

Catalog :

30152

Title :

Mouse Monoclonal Antibody to PSIP1

Species :

Human; Monkey; Rat

Clone :

6E4;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.

Immunogen :

Purified recombinant fragment of human PSIP1 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000

References :

1. J Virol. 2008 Dec;82(23):11555-67. ; 2. Proteins. 2008 Aug;72(2):635-45.

Type :

Monoclonal Antibody

MW :

75kDa

Aliases :

p52; p75; PAIP; DFS70; LEDGF; PSIP2; MGC74712; PSIP1