Mouse Monoclonal Antibody to Oct4 | ProMab 30147 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to Oct4

catalog :

30147

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5F-7

The same clone is also sold as:

OriGene: AM06559SU-N
Invitrogen: MA5-15736
MyBioSource: MBS850273

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30147

Title :

Mouse Monoclonal Antibody to Oct4

Species :

Human

Clone :

5F7;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. (provided by RefSeq).Tissue specificity: Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.

Immunogen :

Synthesized peptide of human Oct4.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. J Biol Chem. 2008 Dec 19;283(51):35825-33. ; 2. Dev Genes Evol. 2008 Oct;218(10):561-6. ; 3. Stem Cells. 2008 Sep;26(9):2419-24.

Type :

Monoclonal Antibody

MW :

45kDa

Aliases :

OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; MGC22487; POU5F1