Mouse Monoclonal Antibody to STK11 | ProMab 30139 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to STK11

catalog :

30139

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4H12

The same clone is also sold as:

Invitrogen: MA5-15729
Abnova: MAB10327
OriGene: AM06552SU-N

reactivity :

human, mouse

application :

western blot, ELISA, flow cytometry

product information

Catalog :

30139

Title :

Mouse Monoclonal Antibody to STK11

Species :

Human; Mouse; Monkey

Clone :

4H12;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Essential role in G1 cell cycle arrest. Phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Tumor suppressor.serine/threonine kinase 11,with two alternatively spliced isoforms,expressed in all tissues,strongly homolog of Xenopus early embryonic kinase 1 (XEEK1),tumor suppressor gene in hamartomas syndrome and in left sided colon carcinogenesis,mutated in sporadic testicular cancer,malignant melanomas and laryngeal tumors,playing a minor role in the development of ovarian carcinoma.LKB1 is a potential target for atherosclerosis and cancer and is shown to be mutated in patients with Peutz-Jeghers cancer syndrome. Tissue specificity: Ubiquitously expressed. Strongest expression in testis and fetal liver.

Immunogen :

Purified recombinant fragment of human STK11 expressed in E. Coli. ; ;

Formulation :

Ascitic fluid containing 0.03% sodium azide. ; ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400

References :

1. Sci Signal. 2009 Jul 21;2(80):ra35. ; 2. Sci Signal. 2009 Sep 1;2(86):pe55.

Type :

Monoclonal Antibody

MW :

54kDa

Aliases :

PJS; LKB1; STK11