Mouse Monoclonal Antibody to BLK | ProMab 30135 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to BLK

catalog :

30135

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1 E6

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, flow cytometry

product information

Catalog :

30135

Title :

Mouse Monoclonal Antibody to BLK

Species :

Human

Clone :

1E6;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development . Activation of B cells by various ligands is accompanied by activation of Blk . It has been suggested that Blk is involved in the control of B cell differentiation and proliferation . Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis . Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response .

Immunogen :

Purified recombinant fragment of human BLK expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. N Engl J Med. 2008 Feb 28;358(9):900-9. ; 2. Genes Immun. 2009 Apr;10(3):219-26. ; 3. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14460-5.

Type :

Monoclonal Antibody

MW :

58kDa

Aliases :

MODY11; MGC10442; BLK