Mouse Monoclonal Antibody to CDKN1C | ProMab 30130 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to CDKN1C

catalog :

30130

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3E3

The same clone is also sold as:

OriGene: AM06544SU-N
Abnova: MAB10550
Invitrogen: MA5-15720

reactivity :

human

application :

western blot, ELISA

product information

Catalog :

30130

Title :

Mouse Monoclonal Antibody to CDKN1C

Species :

Human

Clone :

3E3;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.

Immunogen :

Purified recombinant fragment of human CDKN1C expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide. ;

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000

References :

1. Cell Cycle. 2007 Mar 1;6(5):620-5. ; 2. Oncogene. 2008 Sep 25;27(43):5651-61.

Type :

Monoclonal Antibody

MW :

57kDa

Aliases :

BWS; WBS; p57; BWCR; KIP2; CDKN1C