Mouse Monoclonal Antibody to IGF2BP3 | ProMab 30129 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to IGF2BP3

catalog :

30129

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

#8F11

The same clone is also sold as:

OriGene: AM06543SU-N
Abnova: MAB10694, MAB16327

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

product information

Catalog :

30129

Title :

Mouse Monoclonal Antibody to IGF2BP3

Species :

Human

Clone :

8F11;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism.Tissue specificity: Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines .IMP-3 is a marker for carcinomas and high-grade dysplastic lesions of pancreatic ductal epithelium.

Immunogen :

Purified recombinant fragment of human IGF2BP3 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000

References :

1. Clin Cancer Res. 2008 Mar 15;14(6):1701-6. ; 2. Hepatology. 2008 Oct;48(4):1118-27.

Type :

Monoclonal Antibody

MW :

69kDa

Aliases :

CT98; IMP3; KOC1; IMP-3; VICKZ3; DKFZp686F1078; IGF2BP3