Mouse Monoclonal Antibody to TAB2 | ProMab 30123 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to TAB2

catalog :

30123

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3B5

The same clone is also sold as:

Abnova: MAB10330
Invitrogen: MA5-15713
OriGene: AM06537SU-N

reactivity :

human

application :

western blot, ELISA, flow cytometry

product information

Catalog :

30123

Title :

Mouse Monoclonal Antibody to TAB2

Species :

Human

Clone :

3B5;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.

Immunogen :

Purified recombinant fragment of human TAB2 expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400

References :

1. J Clin Endocrinol Metab. 2006 Mar;91(3):1056-61. ; 2. Sci STKE. 2006 Oct 17;2006(357):re13. ; 3. Am J Hum Genet. 2010 Jun 11;86(6):839-49.

Type :

Monoclonal Antibody

MW :

80kDa

Aliases :

CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; TAB2