Mouse Monoclonal Antibody to CSK | ProMab 30117 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ProMab

product type :

antibody

product name :

Mouse Monoclonal Antibody to CSK

catalog :

30117

quantity :

100μl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5F3

The same clone is also sold as:

OriGene: AM06531SU-N
Novus Biologicals: NBP2-37651
Abnova: MAB10617
Invitrogen: MA5-15707

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry, flow cytometry

product information

Catalog :

30117

Title :

Mouse Monoclonal Antibody to CSK

Species :

Human; Mouse; Monkey; Rat

Clone :

5F3;

lsotype :

Mouse IgG1

Size :

100μl

Storage :

4℃; -20℃ for long term storage

Description :

Carboxy-terminal Src kinase (Csk) is a ubiquitously expressed nonreceptor tyrosine kinase that negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carboxy-terminal tyrosine. Phosphorylated carboxy-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK . This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and exclusive. The SFK carboxy-terminal tyrosine is the only known physiological substrate of Csk .Tissue specificity: Expressed in lung and macrophages.

Immunogen :

Purified recombinant fragment of human CSK expressed in E. Coli.

Formulation :

Ascitic fluid containing 0.03% sodium azide.

Applications :

ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400

References :

1. Nat Genet. 2009 Jun;41(6):677-87. ; 2. Leuk Res. 2009 Sep;33(9):e168-9. ; 3. J Hypertens. 2011 Jan;29(1):62-9.

Type :

Monoclonal Antibody

MW :

50kDa

Aliases :

MGC117393; CSK